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Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
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Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

DOI:
10.3791/63921-v

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05:41 min

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December 16, 2022

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, , ,
1Department of Life Science,Fu Jen Catholic University, 2Department of Medicine,MacKay Medical College, 3Department of Emergency Medicine,MacKay Memorial Hospital, 4Graduate Institute of Injury Prevention and Control,Taipei Medical University, 5MacKay Junior College of Medicine, Nursing, and Management, 6Division of Cardiology, Department of Internal Medicine,Taitung Mackay Memorial Hospital, 7Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine,MacKay Memorial Hospital

Capítulos

  • 00:05Introduction
  • 00:30Preparation Before Surgery
  • 01:37Left Anterior Descending Coronary Artery (LAD Ligation)
  • 04:33Results: Validation of LAD Ligation and Quantification of Infarct Size and Area at Risk
  • 05:18Conclusion

Summary

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Herein, we present a protocol focusing on the quality control of the left anterior descending coronary artery ligation by technically modifying the traditional procedure in rats for acute myocardial ischemia-reperfusion research.

Tags

Ischemia-reperfusionLeft Anterior Descending Coronary ArteryLigationRat ModelThoracotomySurgical ProcedureCotton BallsHolding HooksLigation LoopSnare Loop ControllerAnesthesiaEndotracheal IntubationRib ResectionSurgical WindowPericardium Exposure

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