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使用双极电极通过电点燃杏仁核创建颞叶癫痫小鼠模型
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Neurociência
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JoVE Journal Neurociência
Using a Bipolar Electrode to Create a Temporal Lobe Epilepsy Mouse Model by Electrical Kindling of the Amygdala
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使用双极电极通过电点燃杏仁核创建颞叶癫痫小鼠模型

DOI:
10.3791/64113-v

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09:49 min

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June 29, 2022

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, , , , , , , , ,
1Department of Neurosurgery,Xuanwu Hospital Capital Medical University, 2China Clinical Research Center for Epilepsy Capital Medical University, 3China Beijing Municipal Geriatric Medical Research Center

Capítulos

  • 00:04Introduction
  • 00:54Fabrication of Electrodes
  • 03:54Slip Ring Connection and Circuit Description
  • 04:34Surgery for Implantation
  • 07:00Electrical Kindling
  • 08:13Results: Temporal Lobe Epilepsy Induced by Electrical Kindling of the Amygdala in a Murine Model
  • 09:18Conclusion

Summary

Tadução automática

Tadução automática

杏仁核在颞叶癫痫中起关键作用，颞叶癫痫起源于该结构并从该结构传播。本文详细介绍了具有记录和刺激功能的深部脑电极的制造。它介绍了源自杏仁核的内侧颞叶癫痫模型。

Tags

Bipolar ElectrodeTemporal Lobe EpilepsyMouse ModelElectrical KindlingAmygdalaMesial Temporal LobeLow-costEfficient MethodTeflon-coated Tungsten WireSilver WireRope PinsSolder PasteHeat-shrinkable Tubes

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