Journal
/
/
Konstruktion av en human aorta glatt muskelcell organ-on-a-chip modell för rekapitulering av biomekanisk belastning i aortaväggen
JoVE Journal
Bioengenharia
É necessária uma assinatura da JoVE para visualizar este conteúdo.  Faça login ou comece sua avaliação gratuita.
JoVE Journal Bioengenharia
Construction of a Human Aorta Smooth Muscle Cell Organ-On-A-Chip Model for Recapitulating Biomechanical Strain in the Aortic Wall
DOI:

11:47 min

July 06, 2022

, , , , , , , , , , , ,

Capítulos

  • 00:04Introduction
  • 01:03Primary Human Aortic Smooth Muscle Cell Isolation
  • 02:53Preparation of PDMS Chip
  • 05:29PDMS Chip Surface Treatment and Sterilization
  • 06:12Cell Seeding on the PDMS Chip and Cell Stretching Process
  • 08:23Preparation of the Mechanical Control System
  • 09:30Results: An HASMC‐Organ‐On‐A‐Chip Model to Precisely Control the Parameters of the Biomechanical Strain on the Aortic Wall
  • 11:03Conclusion

Summary

Tadução automática

Här utvecklade vi en human aorta glattmuskelcell organ-on-a-chip-modell för att replikera den in vivo biomekaniska stammen av glattmuskelceller i den mänskliga aortaväggen.

Vídeos Relacionados

Read Article