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Sporing af bispecifik antistofinduceret T-cellehandel ved hjælp af luciferase-transducerede humane T-celler
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Capítulos
- 00:04Introduction
- 00:39Transfection of 293T Cells with Luciferase and Harvest of Viral Supernatant
- 03:22Expansion and Transduction of Activated Human T Cells with Luciferase
- 06:20Engraftment of Luciferase‐Transduced T cells in Immunocompromised Mice and In Vivo Imaging
- 07:41Results: Evaluating the Anti‐Tumor Efficacy and Mechanism of T Cell‐Engaging Bispecific Antibodies
- 09:51Conclusion
Her beskriver vi en metode til transducering af humane T-celler med luciferase for at lette in vivo-sporing af bispecifik antistofinduceret T-cellehandel til tumorer i undersøgelser for at evaluere antitumoreffekten og mekanismen for T-celleengagerende bispecifikke antistoffer.
