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Magnetresonanzgesteuerte, hochintensive, fokussierte, ultraschallerzeugte Hyperthermie: eine praktikable Behandlungsmethode in einem murinen Rhabdomyosarkommodell
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1Institute of Medical Science,University of Toronto, 2Lunenfeld-Tanenbaum Research Institute,Mount Sinai Hospital, 3The Wilfred and Joyce Posluns Centre for Image-Guided Innovation and Therapeutic Intervention,The Hospital for Sick Children, 4Institute of Biomedical Engineering,University of Toronto, 5Leslie Dan Faculty of Pharmacy,University of Toronto, 6Departments of Radiology and Clinical Neurosciences,University of Calgary, 7Department of Radiation Oncology,University of Toronto, 8Department of Medical Imaging,University of Toronto, 9Department of Pediatric Surgery,University of Toronto, 10Department of Surgery,University of Toronto
Capítulos
- 00:04Introduction
- 01:11Intramuscular Cell Injection
- 02:08Screening MRI Scan and HIFU Treatment
- 10:46Results: Average Temperatures and Success Rates of Hyperthermia Treatment and Doxorubicin Levels in the Tumor
- 13:03Conclusion
Hier wird ein Protokoll vorgestellt, um kontrollierte Hyperthermie, die durch magnetresonanzgesteuerten, hochintensiven fokussierten Ultraschall erzeugt wird, zu verwenden, um die Wirkstofffreisetzung von temperaturempfindlichen Liposomen in einem Rhabdomyosarkom-Mausmodell auszulösen.
