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בדיקת יעילות In Vitro ו-In Vivo של ננו-חלקיקי mRNA-ליפידים שנוסחו על ידי ערבוב מיקרופלואידי
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Capítulos
- 00:05Introduction
- 00:50Pre-Formulation Preparation
- 01:51Preparation of the Lipid and Nucleic Acid Mixes
- 02:33Microfluidic Formulation of mRNA-LNPs
- 03:56Post-Formulation Processing and Characterization of the mRNA-LNPs
- 04:51In Vitro Transfection of HepG2 Cells
- 05:55In Vivo Evaluation of mRNA-LNPs in Mice Following Tail Vein Injection
- 07:34Results: Formulation of mRNA-LNPs and the Assessment of In Vitro and In Vivo Performance
- 08:24Conclusion
