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毛滴虫对肺腺癌作用机制的网络药理学预测及实验验证

JoVE Journal
Medicina

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JoVE Journal Medicina

Network Pharmacology Prediction and Experimental Validation of Trichosanthes–Fritillaria thunbergii Action Mechanism Against Lung Adenocarcinoma

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毛滴虫对肺腺癌作用机制的网络药理学预测及实验验证

DOI:

10.3791/64847-v

•

13:18 min

•

March 03, 2023

•

Xu-yi Zhao, Yun-yue Yang, Jing-li Feng, Cui-ling Feng

¹Dongzhimen Hospital affiliated to Beijing University of Chinese Medicine, ²Traditional Chinese Medicine Department,Peking University People’s Hospital

Capítulos

00:04Introduction
01:09Network Pharmacological Prediction
07:14Detection of Cell Viability
09:24Drug Intervention and Sample Collection
10:30Results: Effects of Different Concentrations of Trichosanthes-Fritillaria thunbergii Extract
12:47Conclusion

Summary

Tadução automática

本研究基于网络药理学和实验验证，揭示了毛滴虫治疗肺腺癌的机制 。该研究还表明，PI3K / AKT信号通路在 Trichosanthes-Fritillaria thunbergii 治疗肺腺癌中的作用中起着至关重要的作用。

Tags

Keywords: Network Pharmacology Traditional Chinese Medicine Multicomponent Target Prediction Biological Validation Lung Adenocarcinoma Trichosanthes Fritillaria Thunbergii HERB Database SMILES Swiss ADME Similarity Ensemble Approach GeneCards OMIM

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