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建立小鼠睡眠剥夺装置

JoVE Journal
Medicina
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JoVE Journal Medicina

Establishing a Device for Sleep Deprivation in Mice

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建立小鼠睡眠剥夺装置

DOI:

10.3791/65157-v

•

05:05 min

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September 22, 2023

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Jianqing Chen*¹, Jingze Wei*¹, Xiaoying Ying*², Fan Yang*², Yichao Zhao*², Jun Pu²

¹Department of Cardiology,The First Affiliated Hospital of Bengbu Medical College, ²Department of Cardiology, Ren Ji Hospital, School of Medicine,Shanghai Jiao Tong University

Capítulos

00:00Introduction
00:43Preparation of the Sleep Deprivation Device for Mice
02:44Induction of Sleep Deprivation in Mice
03:32Results: Evaluation of Pathophysiological and Metabolic Changes Associated with Sleep Deprivation in Mice
04:36Conclusion

Summary

Tadução automática

本方案概述了一种用于建立用于诱导小鼠睡眠剥夺的基于摇杆平台的具有成本效益的摇杆平台的装置的方法。该设备已被证明可有效导致脑电图（EEG）证明的睡眠模式中断，以及诱导与睡眠剥夺相关的代谢和分子变化。

Tags

Keywords: Sleep Deprivation Mouse Model Rocker Platform Automated Device Cost-effective Minimally Stressful Motor Connecting Rod Plastic Container Water Bottle Time Contactor

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