/

/

Intracellular Signaling Events and Hormone Secretion in Human Pseudoislets

/

Author Spotlight: Investigating Islet Abnormalities and Function with a Pseudoislet Protocol

JoVE Journal
Biologia

É necessária uma assinatura da JoVE para visualizar este conteúdo. Faça login ou comece sua avaliação gratuita.

JoVE Journal Biologia

Human Pseudoislet System for Synchronous Assessment of Fluorescent Biosensor Dynamics and Hormone Secretory Profiles

Author Spotlight: Investigating Islet Abnormalities and Function with a Pseudoislet Protocol

Intracellular Signaling Events and Hormone Secretion in Human Pseudoislets

DOI:

10.3791/65259-v

•

01:38 min

•

November 03, 2023

•

Tiffany M. Richardson*¹, Yasminye D. Pettway*¹, John T. Walker, Heather A. Nelson, Matthew Ishahak, Gregory Poffenberger, Radhika Aramandla, Conrad Reihsmann, Ashutosh Agarwal, Alvin C. Powers^2,4, Marcela Brissova

¹Department of Molecular Physiology and Biophysics,Vanderbilt University School of Medicine, ²Division of Diabetes, Endocrinology and Metabolism, Department of Medicine,Vanderbilt University Medical Center, ³Department of Biomedical Engineering,University of Miami, ⁴VA Tennessee Valley Healthcare System

Tags

Human Pseudoislet Biosensor Dynamics Hormone Secretory Profiles Type 1 Diabetes Type 2 Diabetes Pancreatic Islet Beta Cell Dysfunction 3D Cell Culture Live-cell Imaging Microfluidic Platform Intracellular Signaling CAMP Insulin Secretion Glucagon Secretion Glucose Homeostasis

Embed

ADICIONAR À PLAYLIST

Usage Statistics

Vídeos Relacionados

Author Spotlight: Investigating Islet Abnormalities and Function with a Pseudoislet Protocol

Synchronous Assessment of Fluorescent Biosensor Dynamics and Hormone Profiles in Human Pseudoislets

Read Article