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Identifying G-Quadruplexes in a DNA Template Using Chemical Mapping
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Author Spotlight: Characterizing DNA G-Quadruplex by Bis-3-Chloropiperidine Based Chemical Mapping
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JoVE Journal Bioquímica
In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines

Author Spotlight: Characterizing DNA G-Quadruplex by Bis-3-Chloropiperidine Based Chemical Mapping

Identifying G-Quadruplexes in a DNA Template Using Chemical Mapping

DOI:
10.3791/65373-v

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01:53 min

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May 12, 2023

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, , ,
1Department of Pharmaceutical and Pharmacological Sciences,University of Padova, 2Institute of Organic Chemistry,Justus Liebig University Giessen

Tags

G-quadruplexDNAChemical MappingBis-3-chloropiperidinesB-CePsTBAThrombin-binding AptamerDNA Secondary StructureIn Vitro CharacterizationNucleic Acid AnalysisAlkylationDNA CleavagePAGEBiologically RelevantTherapeutic Targets

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