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Identifying G-Quadruplexes in a DNA Template Using Chemical Mapping

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In vitro Cartographie chimique des structures de l’ADN G-quadruplex par Bis-3-chloropipéridines

JoVE Journal
Bioquímica

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JoVE Journal Bioquímica

In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines

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In vitro Cartographie chimique des structures de l’ADN G-quadruplex par Bis-3-chloropipéridines

Identifying G-Quadruplexes in a DNA Template Using Chemical Mapping

DOI:

10.3791/65373-v

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01:53 min

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May 12, 2023

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Alice Sosic, Cristina Dal Lago, Richard Göttlich, Barbara Gatto

¹Department of Pharmaceutical and Pharmacological Sciences,University of Padova, ²Institute of Organic Chemistry,Justus Liebig University Giessen

Tags

G-quadruplex DNA Chemical Mapping Bis-3-chloropiperidines B-CePs TBA Thrombin-binding Aptamer DNA Secondary Structure In Vitro Characterization Nucleic Acid Analysis Alkylation DNA Cleavage PAGE Biologically Relevant Therapeutic Targets

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