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Analyzing Mitochondrial Physiology and Bioenergetics in Fruit Flies

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Analyse van de mitochondriale functie in een Drosophila melanogaster PINK1 B9-Null-mutant met behulp van respirometrie met hoge resolutie

JoVE Journal
Bioquímica
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JoVE Journal Bioquímica

Analyzing Mitochondrial Function in a Drosophila melanogaster PINK1^B9-Null Mutant Using High-resolution Respirometry

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Analyse van de mitochondriale functie in een Drosophila melanogaster PINK1 B9-Null-mutant met behulp van respirometrie met hoge resolutie

Analyzing Mitochondrial Physiology and Bioenergetics in Fruit Flies

DOI:

10.3791/65664-v

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02:34 min

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November 10, 2023

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Paula Michelotti*^1,2, Tâmie Duarte*^1,2, Cristiane L. Dalla Corte²

¹Laboratory of Experimental Biochemistry and Toxicology, Department of Biochemistry and Molecular Biology, Center of Natural and Exact Sciences,Federal University of Santa Maria, ²Graduate Program in Biological Sciences: Toxicological Biochemistry,Federal University of Santa Maria

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Keywords: Mitochondrial Function Drosophila Melanogaster PINK1B9-Null Mutant High-resolution Respirometry Parkinson’s Disease Oxidative Phosphorylation Energy Metabolism Mitochondrial Dysfunction Neurodegenerative Diseases

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