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Harnessing iPSC-Derived iTenocytes for Effective Cell-Based Therapy

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Generatie van geïnduceerde pluripotente stamcel-afgeleide iTenocyten via gecombineerde scleraxis-overexpressie en 2D uniaxiale spanning

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Bioengenharia

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JoVE Journal Bioengenharia

Generation of Induced Pluripotent Stem Cell-Derived iTenocytes via Combined Scleraxis Overexpression and 2D Uniaxial Tension

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Generatie van geïnduceerde pluripotente stamcel-afgeleide iTenocyten via gecombineerde scleraxis-overexpressie en 2D uniaxiale spanning

Harnessing iPSC-Derived iTenocytes for Effective Cell-Based Therapy

DOI:

10.3791/65837-v

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01:43 min

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March 01, 2024

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Victoria Yu^2,3, Angela Papalamprou^2,3, Dmitriy Sheyn^2,3,4,5

¹Orthopaedic Stem Cell Research Laboratory,Cedars-Sinai Medical Center, ²Board of Governors Regenerative Medicine Institute,Cedars-Sinai Medical Center, ³Department of Biomedical Sciences,Cedars-Sinai Medical Center, ⁴Department of Orthopedics,Cedars-Sinai Medical Center, ⁵Department of Surgery,Cedars-Sinai Medical Center

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Keywords: Induced Pluripotent Stem Cells ITenocytes Scleraxis Uniaxial Tension Tendon Injury Mesenchymal Stromal Cells Tendon Differentiation Tendon Regeneration Mechanoregulation Biomaterials

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