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JoVE Journal > Biochemistry
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Biochemistry
Isotermisk titreringskalorimetri för utvärdering av PROTACS-inducerad ternär komplex bildning
Published: January 12, 2024
doi:
10.3791/200654
Wei Jiang
,
Holly Soutter
1
Center for the Development of Therapeutics
,
The Broad Institute of MIT and Harvard
Tags
Keywords: Isothermal Titration Calorimetry
PROTACS
Ternary Complex Formation
Protein
DMSO
Micro Calorimeter
Titration
Binary Complex
VHL MZ1
Brd4
Positive Cooperativity
check_url/200654?article_type=t
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Isothermal Titration Calorimetry for Evaluating PROTACS-Induced Ternary Complex Formation.
J. Vis. Exp.
(Pending Publication), e200654, doi:10.3791/200654 (2024).
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