इस प्रकाशन का उद्देश्य मात्रात्मक वेक्टर आधारित विश्लेषण का उपयोग कर पुरानी रीढ़ की हड्डी में चोट के साथ लोगों में सांस की मांसपेशी सक्रियण पैटर्न को चिह्नित करने के लिए एक बहु – मांसपेशी सतह electromyographic दृष्टिकोण पर अपने मूल काम को पेश करने की है.
During breathing, activation of respiratory muscles is coordinated by integrated input from the brain, brainstem, and spinal cord. When this coordination is disrupted by spinal cord injury (SCI), control of respiratory muscles innervated below the injury level is compromised1,2 leading to respiratory muscle dysfunction and pulmonary complications. These conditions are among the leading causes of death in patients with SCI3. Standard pulmonary function tests that assess respiratory motor function include spirometrical and maximum airway pressure outcomes: Forced Vital Capacity (FVC), Forced Expiratory Volume in one second (FEV1), Maximal Inspiratory Pressure (PImax) and Maximal Expiratory Pressure (PEmax)4,5. These values provide indirect measurements of respiratory muscle performance6. In clinical practice and research, a surface electromyography (sEMG) recorded from respiratory muscles can be used to assess respiratory motor function and help to diagnose neuromuscular pathology. However, variability in the sEMG amplitude inhibits efforts to develop objective and direct measures of respiratory motor function6. Based on a multi-muscle sEMG approach to characterize motor control of limb muscles7, known as the voluntary response index (VRI)8, we developed an analytical tool to characterize respiratory motor control directly from sEMG data recorded from multiple respiratory muscles during the voluntary respiratory tasks. We have termed this the Respiratory Motor Control Assessment (RMCA)9. This vector analysis method quantifies the amount and distribution of activity across muscles and presents it in the form of an index that relates the degree to which sEMG output within a test-subject resembles that from a group of healthy (non-injured) controls. The resulting index value has been shown to have high face validity, sensitivity and specificity9-11. We showed previously9 that the RMCA outcomes significantly correlate with levels of SCI and pulmonary function measures. We are presenting here the method to quantitatively compare post-spinal cord injury respiratory multi-muscle activation patterns to those of healthy individuals.
एससीआई और अन्य बीमारियों के बाद सांस की मोटर समारोह का मूल्यांकन करने के लिए मानक नैदानिक परीक्षण फेफड़े समारोह परीक्षण और अमेरिकी रीढ़ की हड्डी में चोट एसोसिएशन हानि स्केल (एआईएस) मूल्यांकन 14,15…
The authors have nothing to disclose.
, क्रेग एच. Neilsen फाउंडेशन (अनुदान 1000056824 – HN000PCG) और राष्ट्रीय – यह काम क्रिस्टोफर और दाना रीव फाउंडेशन (अनुदान CDRF OA2-0802-2), केंटकी रीढ़ की हड्डी और सिर में चोट रिसर्च ट्रस्ट (KSCHIRT अनुदान 9-10A) द्वारा समर्थित किया गया स्वास्थ्य संस्थान: राष्ट्रीय हृदय फेफड़े और रक्त संस्थान (अनुदान 1R01HL103750-01A1).
Name of the Device | Vendor | Product # | Comments |
PowerLab System 16/35 | ADInstruments | PL3516 | Number of units depends on number of channels recorded |
EMG System MA 300 | Motion Lab Systems | MA300-XVI | Number of units depends on number of channels recorded |
Low Pressure Transducer MP45 | Validyne | MP45-40-871 | |
Basic Carrier Demodulator CD15 | Validyne | CD15-A-2-A-1 | |
Air Pressure Manometer | Boehringer | 4103 | Needed for MP45 calibration |
Event Marker | Hand held switch that when pressed gives a DC voltage and sound output (including 5-sec long mark) | ||
Alcohol Wipes | Henry Schein | 1173771 | Needed for electrodes placement |
Electrode Gel | Lectron II | 36-3000-25 | Needed for electrodes placement |
Tagaderm | Henry Schein | 7779152 | Needed for electrodes placement |
Noseclip | Henry Schein | 1089460 | |
T-piece Ventilator Monitoring Circuit with One-way Valves | Alleglance (Airlife) | 1504 | |
Air Tube | UnoMedical | 400E | |
Table 1. List of specific equipment and supplies used for the Respiratory Motor Control Assessment. |