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Nerve-besparende Mid-urethral obstruktion (NEMO) i kvindelige lille Gnavere
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JoVE Journal Medicine
Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Small Rodents

Nerve-besparende Mid-urethral obstruktion (NEMO) i kvindelige lille Gnavere

DOI:
10.3791/55288-v

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07:42 min

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April 25, 2017

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, , ,
1Developmental and Stem Cell Biology, Research Institute,The Hospital for Sick Children, 2Institute of Medical Science,University of Toronto, 3Pediatric Urology,The Hospital for Sick Children, 4Molecular Structure and Function, Research Institute,The Hospital for Sick Children

Chapters

  • 00:05Title
  • 01:25Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Rats
  • 03:25NeMO in Female Mice
  • 05:13Results: Representative NeMO Effects on Mortality, Bladder Mass, and Residual Urine Volume
  • 06:39Conclusion

Summary

Automatic Translation

Automatic Translation

Traditionelle modellering af delvis blæreobstruktion i gnavere er behæftet med dødelighed dyr. En denervering skade fra dissektion omkring den proximale urethra og blærehalsen er ligeledes af stor bekymring. Vi udviklede og evaluerede en sikker og pålidelig mid-urethral obstruktion model, så man undgår manglerne ved den traditionelle model.

Tags

Nerve-sparingMid-urethral ObstructionFemale Small RodentsBladder Outlet ObstructionBladder RemodelingGene ExpressionEpigenetic ChangesBladder Obstruction RecoveryBladder DysfunctionBladder DysmorphismSurgical TechniqueAngiocatheterBlunt DissectionSilk SutureMetal Rod

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