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Direct Tracheal Instillation of Solutes into Mouse Lung
 
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Direct Tracheal Instillation of Solutes into Mouse Lung

Article DOI: 10.3791/1941-v • 04:50 min • August 29th, 2010
August 29th, 2010 •
1,2, 2,3, 1, 2,3
1Department of Physiology, Emory University, 2Center for Respiratory Health, Emory University, 3Department of Medicine, Emory University

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Intratracheal instillations deliver solutes directly into the lungs. This procedure targets the delivery of the instillate into the distal regions of the lung, and is therefore often incorporated in studies aimed at studying alveoli. We provide a detailed survival protocol for performing intratracheal instillations in mice.

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Direct Tracheal Instillation Solutes Mouse Lung Intratracheal Instillations Distal Regions Alveoli Survival Protocol Test Solutes Lung Therapeutics Surfactants Viruses Small Oligonucleotides Tracheal Instillation Protocol Upper Respiratory Tract Hazardous Substances Non-invasive Procedure Physiological Measurements Osmotically Balanced Instillate Volume
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