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JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection

Monocytisolering och monocytdifferentiering till monocythärledda dendritiska celler

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Monocytisolering och monocytdifferentiering till monocythärledda dendritiska celler

De-Sialylated Monocyte-Derived-DCs from Isolated PBMCs Using Sialidase Treatment

Article DOI: 10.3791/200350-v • 06:26 min • October 20th, 2023

October 20th, 2023 •

Vanessa C. C. Luz^1,2, Zélia Silva^1,2, Patrícia Sobral^1,2,3, Ankit Tanwar^4,5, Rachel L. Paterson⁶, Paula A. Videira^1,2,7

¹Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, ²UCIBIO - Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa, ³LAQV and REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, ⁴Department of Microbiology and Immunology, Albert Einstein College of Medicine, ⁵Department of Oncology, Albert Einstein College of Medicine, ⁶Stemmatters, Biotecnologia e Medicina Regenerativa SA, Parque de Ciência e Tecnologia Avepark, Zona Industrial da Gandra, ⁷CDG & Allies - Professionals and Patient Associations International Network (CDG & Allies - PPAIN), Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa

Tags

Monocythärledda dendritiska celler sialylerade fenotyper sialinsyror immunsvarsmodulering immunövervakning glykoimmuna kontrollpunkter immunterapier dendritiska celler (DC) antigenpresenterande celler (APC) mognad av DC sialinsyrainnehåll T-cellsaktivering

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