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PROTACS 유도 삼원 복합체 형성 평가를 위한 등온 적정 열량계
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Biochemistry
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JoVE Journal
Biochemistry
Isothermal Titration Calorimetry for Evaluating PROTACS-Induced Ternary Complex Formation
Please note that all translations are automatically generated.
Click here for the English version.
PROTACS 유도 삼원 복합체 형성 평가를 위한 등온 적정 열량계
DOI:
10.3791/200654-v
•
01:16 min
•
January 12, 2024
•
Wei Jiang
,
Holly Soutter
1
Center for the Development of Therapeutics
,
The Broad Institute of MIT and Harvard
Tags
Isothermal Titration Calorimetry
PROTACS
Ternary Complex Formation
Protein
DMSO
Micro Calorimeter
Titration
Binary Complex
VHL MZ1
Brd4
Positive Cooperativity
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