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Journal
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Biochemistry
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Surface Plasmon Resonance (SPR) for Evaluating PROTACS-Induced Ternary Complex Formation
JoVE Journal
Biochemistry
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JoVE Journal
Biochemistry
Surface Plasmon Resonance (SPR) for Evaluating PROTACS-Induced Ternary Complex Formation
Surface Plasmon Resonance (SPR) for Evaluating PROTACS-Induced Ternary Complex Formation
DOI:
10.3791/200656-v
•
03:36 min
•
January 12, 2024
•
Wei Jiang
,
Holly Soutter
1
Center for the Development of Therapeutics
,
The Broad Institute of MIT and Harvard
Tags
Surface Plasmon Resonance (SPR)
PROTACS
Ternary Complex Formation
VHL
MZ1
BRD4
Binary Complex
Ternary Complex
Cooperativity
Cereblon
PPM1D
Nickel NTA Chip
Regeneration
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