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Heterotopic Heart Transplantation in Mice
JoVE Journal
Biology
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JoVE Journal Biology
Heterotopic Heart Transplantation in Mice
DOI:

23:43 min

July 19, 2007

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Chapters

  • 00:00Title
  • 00:11Introduction
  • 01:19Preparing Recipient Mouse
  • 04:37Removing Donor Heart
  • 08:14Transplanting Heart into Recipient Mouse
  • 19:16Opening Circulation in Transplanted Donor Heart
  • 20:30Suturing Body Wall and Skin
  • 22:30Conclusion

Summary

Automatic Translation

The mouse heterotopic heart transplantation model has been proven by many investigators to be an important method for studying mechanisms of rejection and immune response. However, the techniques involved are still challenging. By modifying standard techniques we have had success with more than 1000 transplants.

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