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Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice
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Chapters
- 01:11Pre-operative Procedures
- 02:31Intracerebral Hemorrhage Surgery
- 05:42Surgical Success Rate and Behavioral Analysis
- 06:27Conclusion
The autologous blood injection model of intracerebral hemorrhage in mice described in this protocol uses the double injection technique to minimize risk of blood reflux up the needle track, no anticoagulants in the pumping system, and eliminates all dead space and expandable tubing in the system.
Tags
Autologous Blood InjectionSpontaneous Intracerebral HemorrhageMice ModelPathophysiology Of InjuryIntracerebral HemorrhageReproducible Animal ModelEffective TherapyStereotaxic InjectionArterial BloodBasal GangliaSpontaneous Hypertensive HemorrhageNeurobehavioral DeficitsPotential Therapeutic AgentsDouble Injection TechniqueBlood RefluxAnticoagulantsDead SpaceExpandable Tubing
