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An in vivo Rodent Model of Contraction-induced Injury and Non-invasive Monitoring of Recovery
JoVE Journal
Medicine
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JoVE Journal Medicine
An in vivo Rodent Model of Contraction-induced Injury and Non-invasive Monitoring of Recovery
DOI:

08:08 min

May 11, 2011

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Chapters

  • 00:05Title
  • 01:25In vivo Injury Model and Measurement of Isometric Torque
  • 04:00In situ Measurement of Whole Muscle Tension
  • 05:38In vivo MR Imaging and/or Spectroscopy of Rodent Skeletal Muscles
  • 06:22Muscle Changes After Injury
  • 07:40Conclusion

Summary

Automatic Translation

An in vivo animal model of injury is described. The method takes advantage of the subcutaneous position of the fibular nerve. Velocity, timing of muscle activation, and arc of motion are all pre-determined and synchronized using commercial software. Post injury changes are monitored in vivo using MR imaging/spectroscopy.

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