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Design of a Cyclic Pressure Bioreactor for the Ex Vivo Study of Aortic Heart Valves
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Chapters
- 00:05Title
- 01:34Tissue Harvest and Preparation
- 02:31Pressure Studies
- 05:27Representative Pressure System Results
- 06:30Conclusion
A cyclic pressure bioreactor capable of subjecting heart valve tissue to physiological and pathological pressure conditions has been designed. A LabVIEW program allows users to control pressure magnitude, amplitude and frequency. This device can be used to study the mechanobiology of heart valve tissue or isolated cells.
Tags
Cyclic Pressure BioreactorEx Vivo StudyAortic Heart ValvesAortic ValveUnidirectional Blood FlowBackflow PreventionInterstitial CellsExtracellular Matrix (ECM)Endothelial Cell MonolayerMechanical StressCalcific LesionsAortic Valve DiseaseHigh Blood PressureValve ReplacementBioprosthetic ValveMechanical ValveValve BiologyPhysical StressesMechanobiologyNative Heart ValvesEngineered Heart ValvesPulsatile BioreactorsCartilage StudyBone StudyBladder Study
