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Solid-fase Submonomer syntese av Peptoid Polymers og deres Self-Assembly inn Svært Bestilt Nanosheets
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Chapters
- 02:55Solid-Phase Submonomer Synthesis of Polypeptoids
- 05:06Cleavage and Side Chain Deprotection
- 07:00Sheet Formation
- 09:49Scanning Electron Microscopy (SEM) of Nanosheets
- 12:34Conclusion
En enkel og generell manuell peptoid syntese metoden involverer basisutstyr og kommersielt tilgjengelige reagenser er skissert, slik at peptoids å være lett syntetiseres i de fleste laboratorier. Syntese, rensing og karakterisering av en amfifile peptoid 36mer er beskrevet, samt dens selv-montering i svært bestilt nanosheets.
Tags
Solid-phase Submonomer SynthesisPeptoid PolymersSelf-assemblyHighly-ordered NanosheetsBiomimeticNon-naturalSequence-specific HeteropolymersProteolysis ResistanceBiological ActivityNanostructuresPeptidesN-substituted GlycinesDe Novo DesignEngineeringBiologically-active MaterialsNanostructured MaterialsPeptoid Synthesis ProtocolLong Chain PolypeptoidsYieldsBasic EquipmentSimple TechniquesCommercially Available ReagentsSubmonomer MethodAcylationDisplacementBromoacetic Acid Activation In SituNN’-diisopropylcarbodiimide AcylationResin-bound Secondary Amine AcylationNucleophilic Displacement
