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Journal / Medicine / Live Imaging of Drug Responses in the Tumor…
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Medicine

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JoVE Journal Medicine
Live Imaging of Drug Responses in the Tumor Microenvironment in Mouse Models of Breast Cancer
 
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Live Imaging of Drug Responses in the Tumor Microenvironment in Mouse Models of Breast Cancer

Article DOI: 10.3791/50088-v • 08:26 min • March 24th, 2013
March 24th, 2013 •
1,2, 2,3, 2
1Watson School of Biological Sciences, 2Cold Spring Harbor Laboratory, 3Departments of Medical Genetics, University of Oslo and Oslo University Hospital

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Summary
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We describe a method for imaging response to anti-cancer treatment in vivo and at single cell resolution.

Tags

Live Imaging Drug Responses Tumor Microenvironment Mouse Models Breast Cancer Tumor-stroma Interactions Anti-cancer Therapies Three-dimensional Co-culture Systems In Vivo In Vitro Settings Direct Visualization Real-time Spinning Disk Confocal Microscopy Anesthetized Mice Drug Distribution Cancer Cell Responses Tumor-stroma Interactions Systemic Therapy Breast Cancer Models Labeling Tumor Components Therapeutic Responses Surgical Procedure Imaging Up To 40 Hours Time-lapse Movies Drug Infiltration Cancer Cell Death Stromal Cell Migration Image Analysis Software
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