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1Respiratory Infection Group,Liverpool School of Tropical Medicine, 2Royal Liverpool and Broadgreen,University Hospital Trust, 3Comprehensive Local Research Network, 4NIHR Biomedical Research Centre in Microbial Diseases,Royal Liverpool and Broadgreen University Hospitals NHS Trust, 5Institute of Lung Health, Respiratory Biomedical Unit,University Hospitals of Leicester NHS Trust & University of Leicester, 6Department of Clinical Infection Microbiology & Immunology, Institute of Infection & Global Health,University of Liverpool
Chapters
- 00:05Title
- 01:41Inoculum Preparation and Volunteer Inoculation
- 03:41Nasal Wash (NW) Procedure
- 04:35Nasal Wash Processing
- 06:11Results: Representative Pneumococcal Blood Agar Plate Cultures and Reported Symptoms in Pneumococcal Inoculum Recipients
- 07:18Conclusion
Experimentell mänsklig pneumokock vagn har en naturlig modell för vagn och en potentiell modell för användning i utvecklingen av vaccin. Denna teknik är värdefull men komplex och innebär kliniska risker genom att införa en patogen i en människa. Vi har utvecklat ett detaljerat protokoll.
