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Assessing Murine Resistance Artery Function Using Pressure Myography
JoVE Journal
Biology
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JoVE Journal Biology
Assessing Murine Resistance Artery Function Using Pressure Myography
DOI:

07:25 min

June 07, 2013

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Chapters

  • 00:05Title
  • 01:30Isolating Mesenteric Artery
  • 02:10Setting Up Mesenteric Artery in the Myograph Chamber
  • 04:36Measuring Vascular Reactivity
  • 06:03Pressure Myography with sGCα1-/- Mice
  • 06:53Conclusion

Summary

Automatic Translation

In pressure myography, an intact small segment of a vessel is mounted onto two small cannulas and pressurized to a suitable luminal pressure. Here, we describe the method to measure vasorelaxation response of the mouse 3rd order mesenteric arteries in c57 and sGCα1-/- mice using pressure myography.

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