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Adult Mouse Venous Hypertension Model: Common Carotid Artery to External Jugular Vein Anastomosis.
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Adult Mouse Venous Hypertension Model: Common Carotid Artery to External Jugular Vein Anastomosis.

Adult Mouse Venous Hypertension Model: Common Carotid Artery to External Jugular Vein Anastomosis.

DOI:
10.3791/50472-v

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08:27 min

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January 27, 2015

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, , , , ,
1Department of Anesthesia and Perioperative Care and Center for Cerebrovascular Research,University of California, San Francisco, 2Department of Neurological Surgery,University of California, San Francisco, 3Department of Neurology,University of California, San Francisco

Chapters

  • 00:05Title
  • 01:13Dissecting the Common Carotid Artery and External Jugular Vein
  • 02:49Preparing the Anastomosis
  • 04:19End-to-side Anastomosis
  • 05:51Results: Representative Anastomosis Results
  • 08:00Conclusion

Summary

Automatic Translation

Automatic Translation

We describe a method for creating a reliable model of cerebral venous hypertension in the adult mouse. This model has been widely described and tested in the rat. This new counterpart in the mice opens the possibility of using genetic modified animals and thereby broadens the applications of the model.

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Keywords: MouseVenous HypertensionArteriovenous FistulaCerebrovascular DiseaseMicrosurgeryTransgenicPathophysiologyBrain AVMDural AVF

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