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A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology
 

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology

Article DOI: 10.3791/50542-v 05:51 min May 6th, 2014
May 6th, 2014

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Summary

Atherosclerosis is a chronic inflammatory process. This manuscript illustrates an easy to use ex vivo model to investigate fresh carotid or coronary artery plaques. The ex vivo model allows for the investigation of potential substances on the inflammatory milieu in human atherosclerotic lesions and results can be analyzed by various methods.

Tags

Keywords: Atherosclerosis Ex Vivo Plaque Model Lesion Biology Inflammatory Processes Atherogenesis Human Immune System In Vitro Cell Experiments Cytokines Chemokines Immunohistochemistry Flow Cytometry ELISA
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