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In utero Measurement of Heart Rate in Mouse by Noninvasive M-mode Echocardiography
JoVE Journal
Medicine
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JoVE Journal Medicine
In utero Measurement of Heart Rate in Mouse by Noninvasive M-mode Echocardiography
DOI:

08:01 min

November 22, 2013

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Chapters

  • 00:05Title
  • 01:08Ultrasound System and Station Preparation
  • 02:33Mouse Preparation
  • 03:58Embryo Identification
  • 04:46Heart Rate Measurement
  • 06:35Embryo Genotyping
  • 07:21Impact of Furin, a Serine Protease on Embryonic Heart Rate
  • 07:43Conclusion

Summary

Automatic Translation

Ultra-high frequency ultrasound is a powerful live imaging tool to examine cardiac abnormalities in small animals. Its noninvasiveness allows maintaining the physiologic state of embryos. Herein, we show the use of M-mode ultrasound to measure the heart rates of embryos at E18.5 in utero.

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