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Udnyttelsen af ​​Oropharyngeal Intratracheal PAMP Administration og Bronchoalveolære at evaluere Host immunrespons i mus
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JoVE Journal Immunology and Infection
The Utilization of Oropharyngeal Intratracheal PAMP Administration and Bronchoalveolar Lavage to Evaluate the Host Immune Response in Mice

Udnyttelsen af ​​Oropharyngeal Intratracheal PAMP Administration og Bronchoalveolære at evaluere Host immunrespons i mus

DOI:
10.3791/51391-v

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12:27 min

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April 02, 2014

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1Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine,Virginia Polytechnic Institute and State University

Chapters

  • 00:05Title
  • 01:24Serum and Bronchoalveolar Lavage Fluid (BALF) Collection
  • 05:27Histopathology Preparation
  • 07:52Results: Representative Immuno- and Histopathological Analyses of LPS-treated Lung Tissue
  • 12:00Conclusion

Summary

Automatic Translation

Automatic Translation

Reaktionen på patogeninfektion værtsimmunrespons er en stramt reguleret proces. Ved hjælp af en lipopolysaccharid lunge eksponering model i mus, er det muligt at foretage høj opløsning evalueringer af de komplekse mekanismer, der er forbundet med sygdom patogenese.

Tags

Oropharyngeal Intratracheal AdministrationBronchoalveolar LavageHost Immune ResponseLipopolysaccharidePAMPAcute Lung InflammationInnate ImmunityHost-pathogen InteractionMouse Model

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