Journal
/
Bioengineering
/
A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology
JoVE Journal
Bioengineering
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Bioengineering
A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology

A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology

DOI:
10.3791/51454-v

•

16:46 min

•

June 03, 2014

•

, , , ,
1Centre for Interdisciplinary NanoPhysics, Department of Physics,University of Ottawa, 2University of Ottawa Heart Institue,University of Ottawa, 3Libin Cardiovascular Institute of Alberta,University of Calgary, 4Department of Biology,University of Ottawa, 5Institute for Science, Society and Policy,University of Ottawa

Chapters

  • 00:05Title
  • 01:57Mechanical Deformation of Single Cells
  • 08:45Stiffness Measurement of Small Caliber Vessels
  • 11:06Results: The Biaxial Stretching Platform Can Be Used to Investigate Cell Stretching and Assess Vessel Stiffness
  • 16:13Conclusion

Summary

Automatic Translation

Automatic Translation

We present in this article a novel stretching platform that can be used to investigate single cell responses to complex anisotropic biaxial mechanical deformation and quantify the mechanical properties of biological tissues.

Tags

Keywords: Biaxial StretchingCell MechanicsMechanobiologyStretching PlatformVoice Coil MotorsFlexible SubstrateForce Load CellMicroscopy Imaging

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/51454?article_type=v

Creating Two-Dimensional Patterned Substrates for Protein and Cell Confinement
check_url/51454?article_type=v

Sandwich-like Microenvironments to Harness Cell/Material Interactions
check_url/51454?article_type=v

A Microfluidic Platform for High-throughput Single-cell Isolation and Culture
check_url/51454?article_type=v

Melt Electrospinning Writing of Three-dimensional Poly(ε-caprolactone) Scaffolds with Controllable Morphologies for Tissue Engineering Applications
check_url/51454?article_type=v

An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing
check_url/51454?article_type=v

A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects
check_url/51454?article_type=v

A Microfluidic Platform for Stimulating Chondrocytes with Dynamic Compression
check_url/51454?article_type=v

Establishing Single-Cell Based Co-Cultures in a Deterministic Manner with a Microfluidic Chip
check_url/51454?article_type=v

Simultaneous Quantification of Selected Kynurenines Analyzed by Liquid Chromatography-Mass Spectrometry in Medium Collected from Cancer Cell Cultures
check_url/51454?article_type=v

Developing 3D Organized Human Cardiac Tissue within a Microfluidic Platform

Read Article