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测量脊髓突触前抑制小鼠背根电位记录<em>在体内</em
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JoVE Journal Neuroscience
Measuring Spinal Presynaptic Inhibition in Mice By Dorsal Root Potential Recording In Vivo
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测量脊髓突触前抑制小鼠背根电位记录<em>在体内</em

DOI:
10.3791/51473-v

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09:48 min

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March 29, 2014

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,
1Hans Berger Department of Neurology,Jena University Hospital, Jena, Germany, 2Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC),Jena University Hospital, Jena, Germany

Chapters

  • 00:00Title/Introduction
  • 02:23Preparations for Experiment
  • 03:19Animal Preparation for Recording Procedure
  • 06:00Separating Dorsal Roots and Electrode Positioning
  • 07:35Example Data
  • 08:35Conclusion

Summary

Automatic Translation

Automatic Translation

GABA能突触前抑制是在脊髓电机和脊髓网络感官信号集成的重要功能强大的抑制机制。底层的初级传入去极化可以通过记录背根电位（DRP）来测量。在这里，我们证明在体内录音DRP小鼠的方法。

Tags

Keywords: Presynaptic InhibitionDorsal Root PotentialPrimary Afferent DepolarizationGABAergicSpinal CordIn VivoMicePainMotor HyperexcitabilitySuction ElectrodeTransgenic Mouse ModelsSpinal Pathophysiology

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