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在小鼠模型自发转移性肾细胞癌（MRCC）肾切除
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JoVE Journal Medicine
Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
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在小鼠模型自发转移性肾细胞癌（MRCC）肾切除

DOI:
10.3791/51485-v

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11:27 min

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April 29, 2014

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, , , ,
1Genitourinary Section, Department of Medicine,Roswell Park Cancer Institute, 2Biological Sciences Platform,Sunnybrook Research Institute

Chapters

  • 00:05Title
  • 02:13Orthotopic Kidney Tumor Implantation
  • 05:37Nephrectomy/Primary Tumor Removal
  • 06:51Monitoring Metastatic Progression and Localization at Endpoint
  • 09:47Results: Assessment of Metastasis Location and Severity
  • 10:19Conclusion

Summary

Automatic Translation

Automatic Translation

可用于临床相关设置评估治疗自发性转移性肾细胞癌（RCC）疾病进展的模型。该协议显示不同的程序原位肾肿瘤细胞植入，适当性肾切除术，最后概述了视觉和生物发光的负担转移和本地化得分尸检指南。

Tags

Metastatic Renal Cell CarcinomaMRCCMouse ModelNephrectomyOrthotopic Tumor ImplantationSyngeneic ModelBioluminescent ImagingMetastatic Disease ProgressionTherapeutic Testing

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