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Journal / Medicine / Non-invasive Imaging and Analysis of Cerebral…
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Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG
 

Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG

Article DOI: 10.3791/51495-v • 10:31 min • December 28th, 2014
December 28th, 2014 •
1,2, 3, 4, 1, 4, 1,2, 3,4,5
1W. M. Keck Center for Transgene Research, University of Notre Dame, 2Department of Chemistry and Biochemistry, University of Notre Dame, 3Notre Dame Integrated Imaging Facility, University of Notre Dame, 4Department of Biological Sciences, University of Notre Dame, 5Harper Cancer Research Institute, University of Notre Dame

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Summary
Automatic Translation

Brain damage resulting from cerebral ischemia may be non-invasively imaged and studied in rats using pre-clinical positron emission tomography coupled with the injectable radioactive probe, 18F-fluorodeoxyglucose. Further, the use of modern software tools that include volume of interest (VOI) brain templates dramatically increase the quantitative information gleaned from these studies.

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Keywords: Cerebral Ischemia Stroke Positron Emission Tomography FDG-PET Middle Cerebral Artery Occlusion MCAO Rat Model 3D Visualization VOI Template Atlas
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