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A Novel Method of Drug Administration to Multiple Zebrafish (Danio rerio) and the Quantification of Withdrawal
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Neuroscience
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JoVE Journal Neuroscience
A Novel Method of Drug Administration to Multiple Zebrafish (Danio rerio) and the Quantification of Withdrawal

A Novel Method of Drug Administration to Multiple Zebrafish (Danio rerio) and the Quantification of Withdrawal

DOI:
10.3791/51851-v

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10:52 min

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November 12, 2014

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, ,
1Department of Psychology,MacEwan University

Chapters

  • 00:05Title
  • 01:51Prepare Dosing Tanks, Solutions and Administration Schedule
  • 03:39Netting Fish and Ethanol Administration Pocedure
  • 04:38Behavioral Testing
  • 07:05Analysis
  • 08:26Results: Representative Trackplots and Heatmaps of Ethanol Dosing Procedure on Three Groups of Zebrafish after Two Days Withdrawal
  • 10:06Conclusion

Summary

Automatic Translation

Automatic Translation

A novel method for reducing variability when exposing fish to drugs is explained. Fish exposed to various patterns of ethanol exposure were found to have altered anxiety levels during withdrawal in a light/dark scototaxic assay.

Tags

Keywords: ZebrafishDrug AdministrationSpawning InsertLight/dark TestWithdrawal AnxietyEthanol ExposureBehavioral Testing

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