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JoVE Journal Neuroscience
The Analysis of Neurovascular Remodeling in Entorhino-hippocampal Organotypic Slice Cultures
 

The Analysis of Neurovascular Remodeling in Entorhino-hippocampal Organotypic Slice Cultures

Article DOI: 10.3791/52023-v • 08:27 min • October 23rd, 2014
October 23rd, 2014 •
1, 2, 1
1Anatomical Institute, Department of Biomedicine Basel, University of Basel, 2Department of Neonatology, University Children's Hospital (UKBB), University of Basel

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Summary
Automatic Translation

A protocol for entorhino-hippocampal organotypic slice cultures, which allows reproducing many aspects of ischemic brain injury, is presented. By studying changes of the neurovasculature in addition to changes in the neurons, this protocol is a versatile tool to study plastic changes in neural tissue after injury.

Tags

Brain Ischemia Neurovascular Remodeling Organotypic Slice Cultures Oxygen And Glucose Deprivation In Vitro Model Neuronal Damage Vascular Changes
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