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种植<em> Heligmosomoides Polygyrus：</em>免疫调节线虫寄生虫及其分泌产物

JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection

Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products

Please note that all translations are automatically generated. Click here for the English version.

种植<em> Heligmosomoides Polygyrus：</em>免疫调节线虫寄生虫及其分泌产物

DOI:

10.3791/52412-v

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12:40 min

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April 06, 2015

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Chris J. C. Johnston, Elaine Robertson, Yvonne Harcus, John R. Grainger, Gillian Coakley, Danielle J. Smyth, Henry J. McSorley, Rick Maizels

¹Institute of Immunology and Infection Research,University of Edinburgh, ²Manchester Collaborative Centre for Inflammation Research

Chapters

00:05Title
01:49Infection of Mice by Gavage
02:55Collection of Adult H. polygyrus Worms
06:06Propagation of H. polygyrus Life Cycle
07:22Setting Up Cultures for HES
07:57Preparation of HES
10:24Results: The H. polygyrus Life Cycle Can Be Maintained Long Term and Their Excretory-secretory Products Collected
11:33Conclusion

Summary

Automatic Translation

Heligmosomoides polygyrus是鼠类线虫具有强大的免疫调节功能，非常类似于那些高度流行的人类寄生虫感染。在这里，我们描述了一个协议，用于长期维持H的polygyrus生命周期。

Tags

Heligmosomoides Polygyrus Nematospiroides Dubius H. Bakeri Gastrointestinal Helminth Immunomodulatory Chronic Infection Mice Helminth-derived Immune Regulation Allergy Autoimmunity L3 Larvae Adult Parasites Excretory-secretory Products HES

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