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Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
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Bioengineering
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JoVE Journal Bioengineering
Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

DOI:
10.3791/52797-v

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10:32 min

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March 26, 2015

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, , , , , ,
1Department of Orthopaedic Surgery,University of California Los Angeles, 2Department of Bioengineering,University of California Los Angeles

Chapters

  • 00:05Title
  • 01:51Preparation of Electrospun Polycaprolactone Scaffolds
  • 04:42Rat Surgery
  • 08:28Results: Representative Implanted Electrospun Graft Analysis
  • 09:28Conclusion

Summary

Automatic Translation

Automatic Translation

Animal models are important tools for the evaluation of tissue-engineered grafts. This paper presents the protocol for preparing an electrospun biodegradable polymer graft for use in anterior cruciate ligament tissue engineering, as well as a surgical protocol for implantation in a rat model.

Tags

Anterior Cruciate LigamentACLGraftPolycaprolactoneAthymic Rat ModelIntra-articularBiomechanical TestingHistology

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