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Journal / Behavior / Using the Activity-based Anorexia Rodent Model to …
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Behavior

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JoVE Journal Behavior
Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa
 

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa

Article DOI: 10.3791/52927-v • 07:46 min • October 22nd, 2015
October 22nd, 2015 •
1, 1, 1
1Center for Neural Science, New York University

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Here we present a protocol to induce activity-based anorexia (ABA) in female adolescent mice. ABA is a condition of hyperactivity evoked by imposing food restriction on rodents with access to a running wheel. This phenomenon is being used as a model to study the underlying neurobiology of anorexia nervosa.

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Keywords: Activity-based Anorexia Anorexia Nervosa Rodent Model Neurobiology Hyperactivity Food Restriction Running Wheel Circadian Rhythm C57BL/6 Mice
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