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Elektro på Isolerade hjärnstammen-ryggmärgen Förberedelser från nyfödda Gnagare Tillåter Neural Respiratory Network Output inspelning
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Electrophysiology on Isolated Brainstem-spinal Cord Preparations from Newborn Rodents Allows Neural Respiratory Network Output Recording
DOI:

05:28 min

November 19, 2015

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Chapters

  • 00:05Title
  • 01:11Dissection
  • 02:56Recording
  • 04:26Results: Examples of Recordings Obtained from Brainstem-spinal Cord Preparations
  • 04:59Conclusion

Summary

Automatic Translation

The central respiratory drive is located in the brainstem. Spontaneous respiratory motor output from an isolated brainstem-spinal cord is recorded by placing an electrode on the fourth ventral root. This experimental approach is valuable for pharmacological investigations or the assessment of respiratory challenges and genetic manipulations on rhythmic motor behavior.

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