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Chapters
- 00:05Title
- 02:36Preliminary Fabrication of Micropipettes, Restrainers, and Blockers
- 04:11Arranging Mesentery Tissue and Identification of Microvessel
- 05:28Fill Micropipiette and Mount in Holder
- 06:55Microcannulation and Microvascular Pressure Measurement
- 08:26Microocclusion and Collection of Data
- 09:43Results: Microvessel Permeability Measurements
- 11:36Conclusion
The modified Landis technique enables paired measurement of the hydraulic conductivity of individual microvessels in the mesentery of normal and genetically modified rats under control and test conditions using microperfusion techniques. It provides a convenient method to evaluate mechanisms that regulate microvessel permeability and transvascular exchange under physiological conditions.
