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Behandling SCA1 Mus med vandopløselige forbindelser til uspecifikt Boost mitokondriefunktionen
JoVE Journal
Medicine
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JoVE Journal Medicine
Treating SCA1 Mice with Water-Soluble Compounds to Non-Specifically Boost Mitochondrial Function
DOI:

11:47 min

January 22, 2017

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Chapters

  • 00:05Title
  • 01:25Footprint Analysis
  • 03:00Beam Analysis
  • 04:16Accelerating Rotarod
  • 05:35Immunopathology Assay
  • 09:39Results: Treatment Scheme and Representative Data from the Footprint Assay, Beam Assay and Accelerating Rotarod
  • 10:59Conclusion

Summary

Automatic Translation

We present a biochemical and behavioral protocol to evaluate the efficacy of mitochondria-targeted water-soluble compounds for the treatment of Spinocerebellar ataxia type 1 (SCA1) and other cerebellar neurodegenerative diseases.

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