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Den løbebånd Træthed Test: En enkel, High-throughput Assay af Træthed-lignende adfærd for musen
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Behavior
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JoVE Journal Behavior
The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse

Den løbebånd Træthed Test: En enkel, High-throughput Assay af Træthed-lignende adfærd for musen

DOI:
10.3791/54052-v

•

09:25 min

•

May 31, 2016

•

, ,
1Laboratory of Endocrinology and Receptor Biology,National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 2Murine Phenotyping Core,National Heart, Lung, and Blood Institute, National Institutes of Health

Chapters

  • 00:05Title
  • 00:48Treadmill Set Up
  • 01:43Treadmill Training
  • 05:04Treadmill Fatigue Test
  • 07:11Results: Fatigue Testing with 5-FU Treatment
  • 08:51Conclusion

Summary

Automatic Translation

Automatic Translation

Fatigue is a common, undertreated and frequently poorly-understood symptom in many diseases and disorders. New preclinical assays of fatigue may help to improve current understanding and future treatment of fatigue. To that end, the current protocol provides a novel means of measuring fatigue-like behavior in the mouse.

Tags

TreadmillFatigueBehaviorMouseAssayInterventionAnti-fatigueTrainingTestingShock GridSpeedWalkingExploring

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