Journal
/
Neuroscience
/
Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry
JoVE Journal
Neuroscience
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Neuroscience
Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry

Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry

DOI:
10.3791/54201-v

•

11:19 min

•

September 06, 2016

•

, , , , , , , ,
1Department of Materials Science and Engineering,Massachusetts Institute of Technology, 2Department of Biological Engineering,Massachusetts Institute of Technology, 3Department of Mechanical Engineering,Massachusetts Institute of Technology, 4Department of Neurology, The F.M. Kirby Neurobiology Center,Boston Children’s Hospital, Harvard Medical School

Chapters

  • 00:05Title
  • 01:24Atomic Force Microscope-enabled Indentation
  • 03:11Impact Indentation
  • 07:25Rheology
  • 09:04Results: Measuring Multiscale Mechanical Properties of Brain Tissue
  • 10:10Conclusion

Summary

Automatic Translation

Automatic Translation

We present a set of techniques to characterize the viscoelastic mechanical properties of brain at the micro-, meso-, and macro-scales.

Tags

Keywords: Atomic Force MicroscopyImpact IndentationRheometryViscoelastic PropertiesMechanical CharacterizationMultiple SclerosisAutismBrain InjuryCreep Compliance

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/54201?article_type=v

Preparation of Mouse Brain Tissue for Immunoelectron Microscopy
check_url/54201?article_type=v

Focussed Ion Beam Milling and Scanning Electron Microscopy of Brain Tissue
check_url/54201?article_type=v

Functional Neuroimaging Using Ultrasonic Blood-brain Barrier Disruption and Manganese-enhanced MRI
check_url/54201?article_type=v

Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration
check_url/54201?article_type=v

The Olfactory System as a Model to Study Axonal Growth Patterns and Morphology In Vivo
check_url/54201?article_type=v

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
check_url/54201?article_type=v

Using Fluorescence Activated Cell Sorting to Examine Cell-Type-Specific Gene Expression in Rat Brain Tissue
check_url/54201?article_type=v

Peering at Brain Polysomes with Atomic Force Microscopy
check_url/54201?article_type=v

Analysis of Brain Mitochondria Using Serial Block-Face Scanning Electron Microscopy
check_url/54201?article_type=v

Preparation of Non-human Primate Brain Tissue for Pre-embedding Immunohistochemistry and Electron Microscopy

Read Article