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JoVE Journal
Immunology and Infection

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Urinary Tract Infection in a Small Animal Model
 

Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice

Article DOI: 10.3791/54432-v 10:23 min December 1st, 2017
December 1st, 2017

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Summary

The established model of transurethral catheterization of mice allows the study of bladder pathologies, including urinary tract infection, but can only be performed in females. A new model of male transurethral instillation, presented here, will enable research in an area marked by strong clinical and epidemiological differences between the sexes.

Tags

Keywords: Urinary Tract Infection Small Animal Model Transurethral Catheterization Male And Female Mice Mucosal Immunology Uropathogenic E. Coli Inoculum Bladder Instillation
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