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The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
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The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)

DOI:
10.3791/54504-v

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06:49 min

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November 20, 2016

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, ,
1Department of Ophthalmology and Visual Sciences,University of Maryland-Baltimore School of Medicine, 2Anatomy and Neurobiology,University of Maryland-Baltimore School of Medicine

Chapters

  • 00:05Title
  • 01:15Experimental Set-up
  • 02:33rNAION Model Generation
  • 05:09Results: Retinal and Optic Nerve Analysis 2 Days after rNAION Induction
  • 06:02Conclusion

Summary

Automatic Translation

Automatic Translation

The following report describes how to replicate the rodent model of nonarteritic anterior ischemic optic neuropathy (rNAION), using the appropriate dye, contact lens and laser parameters. We also reveal the appropriate steps for evaluating the rNAION lesion in vivo.

Tags

Rodent ModelNonarteritic Anterior Ischemic Optic NeuropathyRNAIONOptic Nerve StrokeNeuroprotective AgentsEdemaInflammationOptic Nerve DamageExo-ischemiaRose BengalNeodymium Yttrium Aluminum Garnet LaserAnesthesiaPupil DilationOphthalmic Coupling

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