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לחקר ויראלי וקטורים בתוך אוכלס מחדש תלת מימדי הכבד דגם עם הקו Cell Carcinoma Hepatocellular האדם HepG2
JoVE Journal
Cancer Research
This content is Free Access.
JoVE Journal Cancer Research
Study of Viral Vectors in a Three-dimensional Liver Model Repopulated with the Human Hepatocellular Carcinoma Cell Line HepG2
DOI:

09:13 min

October 24, 2016

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Chapters

  • 00:05Title
  • 01:08Recellularization of Extracellular Matrix (ECM) of a Rat Liver
  • 04:28Transduction of the Recellularized Rat Liver
  • 05:59Assessment of the Recellularized Transduced Rat Liver
  • 07:14Results: Recellularization Assessment and Transduction Efficiency
  • 08:39Conclusion

Summary

Automatic Translation

The recellularized extracellular matrix of a decellularized rat liver can be used as a humanized, three-dimensional ex vivo model to study the distribution and transgene expression of a virus or viral vector.

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