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Studier av virale vektorer i et tredimensjonalt Liver Modell repopulated med Human leverkreft cellelinje HepG2
JoVE Journal
Cancer Research
This content is Free Access.
JoVE Journal Cancer Research
Study of Viral Vectors in a Three-dimensional Liver Model Repopulated with the Human Hepatocellular Carcinoma Cell Line HepG2
DOI:

09:13 min

October 24, 2016

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Chapters

  • 00:05Title
  • 01:08Recellularization of Extracellular Matrix (ECM) of a Rat Liver
  • 04:28Transduction of the Recellularized Rat Liver
  • 05:59Assessment of the Recellularized Transduced Rat Liver
  • 07:14Results: Recellularization Assessment and Transduction Efficiency
  • 08:39Conclusion

Summary

Automatic Translation

The recellularized extracellular matrix of a decellularized rat liver can be used as a humanized, three-dimensional ex vivo model to study the distribution and transgene expression of a virus or viral vector.

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